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澤井 信彦Sawai Nobuhiko
講師


研究テーマ

・ 視床下部の比較神経解剖学
・ 行動神経内分泌に関わる脳内コネクトーム解析
・ 水チャネルの役割と分子機構


略歴

1992年  東京理科大学理工学部応用生物科学科卒業
1998年  筑波大学大学院医学博士課程修了
1998年  日本医科大学医学部 解剖学(第二)助手
2011年  群馬大学医学部 生体構造学講座 助教
2015年  日本医科大学医学部 解剖学(分子解剖学)講師 
2018年  日本医科大学医学部 形態解析研究室 講師
2020年  日本医科大学医学部 解剖学(生体構造学)講師


論文

Phosphorylation and dephosphorylation of aquaporin-2 at serine 269 and its subcellular distribution during vasopressin-induced exocytosis and subsequent endocytosis in the rat kidney. Kinue Shimizu, Megumi Sano, Aoi Kita, Nobuhiko Sawai, Akiko Iizuka-Kogo, Hiroshi Kogo, Takeo Aoki, Kuniaki Takata, Toshiyuki Matsuzaki. Arch Histol Cytol 77 25 - 38 2017

Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development: possible role in convergent extension. Iizuka-Kogo A, Senda T, Akiyama T, Shimomura A, Nomura R, Hasegawa Y, Yamamura K, Kogo H, Sawai N, Matsuzaki T. PloS one 10(4) e0123965 2015

Neurokinin B- and kisspeptin-positive fibers as well as tuberoinfundibular dopaminergic neurons directly innervate periventricular hypophyseal dopaminergic neurons in rats and mice. Nobuhiko Sawai, Norio Iijima, Hitoshi Ozawa, Toshiyuki Matsuzaki. Neurosci Res. 10 - 18 2014

Effects of repeated administration of pilocarpine and isoproterenol on aquaporin-5 expression in rat salivary glands. Susa T, Sawai N, Aoki T, Iizuka-Kogo A, Kogo H, Negishi A, Yokoo S, Takata K, Matsuzaki T. Acta histochemica et cytochemica. 46(6) 187 - 197 2013

Immunofluorescent histochemical and ultrastructural studies on the innervation of kisspeptin/neurokinin B neurons to tuberoinfundibular dopaminergic neurons in the arcuate nucleus of rats. Nobuhiko Sawai, Norio Iijima, Ken Takumi, Keisuke Matsumoto, Hitoshi Ozawa. Neurosci Res. 74(1) 10 - 16 2012

An Immunohistochemical Study on the Expressional Dynamics of Kisspeptin Neurons Relevant to GnRH Neurons Using a Newly Developed Anti-kisspeptin Antibody. Norio Iijima, Ken Takumi, Nobuhiko Sawai, Hitoshi Ozawa. J Mol Neurosci. 43(2) 146 - 154 2011

Immunohistochemical Localization of the Water Channels AQP4 and AQP5 in the Rat Pituitary Gland. Toshiyuki Matsuzaki, Yuki Inahata, Nobuhiko Sawai, Chun-Ying Yang, Makito Kobayashi, Kuniaki Takata, Hitoshi Ozawa. Acta histochemica et cytochemica. 44(6) 259 - 266 2011

Developmental and aging change of orexin-A and -B immunoreactive neurons in the male rat hypothalamus. Sawai N, Ueta Y, Nakazato M, Ozawa H. Neurosci lett. 468(1) 51 - 55 2010

The influence of dietary restriction on the development of diabetes and pancreatitis in female WBN/Kob-fatty rats. Akimoto T, Terada M, Shimizu A, Sawai N, Ozawa H. Experimental animals 59(5) 623 - 630 2010

Characterization of a novel congenic strain of diabetic fatty (WBN/Kob-Lepr(fa)) rat. Akimoto T, Nakama K, Katsuta Y, Zhang XJ, Ohsuga M, Ishizaki M, Sawai N, Ozawa H. Biochem Biophys Res Commun. 366(2) 556 - 562 2008

A new interpretation on the homology of the teleostean telencephalon based on hodology and a new eversion model. Naoyuki Yamamoto, Yuji Ishikawa, Masami Yoshimoto, Hao-Gang Xue, Nurmamat Bahaxar, Nobuhiko Sawai, Chun-Ying Yang, Hitoshi Ozawa, Hironobu Ito. Brain Behav Evol. 69(2) 96 - 104 2007

Projections of the sensory trigeminal nucleus in a percomorph teleost, tilapia (Oreochromis niloticus). HG Xue, N Yamamoto, CY Yang, G Kerem, M Yoshimoto, N Sawai, H Ito, H Ozawa. J Comp Neurol.495(3) 279 - 298 2006

Fiber connections of the lateral valvular nucleus in a percomorph teleost, tilapia (Oreochromis niloticus). CY Yang, M Yoshimoto, HG Xue, N Yamamoto, K Imura, N Sawai, Y Ishikawa, H Ito J Comp Neurol. 474(2) 209 - 226 2004

Fiber connections of the torus longitudinalis in a teleost: Cyprinus carpio re-examined. Ito H, Yamamoto N, Yoshimoto M, Sawai N, Yang CY, Xue HG, Imura K. J Comp Neurol. 457(2) 202 - 211 2003

Topographical organization of an indirect telencephalo-cerebellar pathway through the nucleus paracommissuralis in a teleost, Oreochromis niloticus. Imura K, Yamamoto N, Sawai N, Yoshimoto M, Yang CY, Xue HG, Ito H. Brain Behav Evol. 61(2) 70 - 90 2003

Fiber connections of the corpus mamillare in a percomorph teleost, tilapia Oreochromis niloticus. N Sawai, N Yamamoto, M Yoshimoto, H Ito. Brain Behav Evol. 55(1) 1 - 13 2000

Visual thalamotelencephalic pathways in the sturgeon Acipenser, a non-teleost actinopterygian fish. JS Albert, N Yamamoto, M Yoshimoto, N Sawai, H Ito. Brain Behav Evol. 53(3) 156 - 172 1999

Preoptic gonadotropin-releasing hormone (GnRH) neurons innervate the pituitary in teleosts. N Yamamoto, IS Parhar, N Sawai, Y Oka, H Ito. Neurosci Res. 31(1) 31 - 38 1998

Telencephalic ascending gustatory system in a cichlid fish, Oreochromis (Tilapia) niloticus. Yoshimoto M, Albert JS, Sawai N, Shimizu M, Yamamoto N, Ito H. Yoshimoto M, Albert JS, Sawai N, Shimizu M, Yamamoto N, Ito H. J Comp Neurol. 392(2) 209 - 226 1998

Gonadotropin-releasing hormone neurons in the gourami midbrain: a double labeling study by immunocytochemistry and tracer injection. Yamamoto N, Oka Y, Yoshimoto M, Sawai N, Albert JS, Ito H. Neurosci Lett. 240(1) 50 - 52 1998

Terminal morphology of two branches arising from a single stem-axon of pretectal (PSm) neurons in the common carp. Ito H, Yoshimoto M, Albert JS, Yamane Y, Yamamoto N, Sawai N, Kaur A. J Comp Neurol. 378(3) 379 - 388 1997